ea0016p290 | Endocrine tumours | ECE2008
Trojanowicz Bogusz
, Winkler Anja
, Hammje Kathrin
, Chen Zhouxun
, Sekulla Carsten
, Glanz Dagobert
, Schmutzler Cornelia
, Mentrup Birgit
, Hombach-Klonisch Sabine
, Klonisch Thomas
, Finke Rainer
, Kohrle Josef
, Dralle Henning
, Hoang-Vu Cuong
Retinoic acid (RA) acts as an anti-proliferative and re-differentiation agent in the therapy of thyroid carcinoma but the molecular mechanisms by which RA mediates these effects are not well understood. We have investigated the effect of RA on the production and post-translational modification of the two ENO1 transcriptional products in the human follicular thyroid carcinoma cell line FTC-133. The single ENO1 transcript encodes a 48 kDa ENO1 with its unique N-terminal enolase ...